Balkan Endemic Nephropathy and Associated Urothelial Cancer: Current Status and Future Research
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چکیده
_______________________________ Correspondence to: Goce B Spasovski, MD, PhD, Department of Nephrology, Clinical Center Skopje, Vodnjanska 17, 1000 Skopje, Macedonia, Fax: +389 2 3220 935 or +389 2 3231 501, E-mail: [email protected] Balkan Endemic Nephropathy and Associated Urothelial Cancer: Current Status and Future Research V. Stefanovic Institute of Nephrology and Hemodialysis, Faculty of Medicine, Nis, Serbia and Montenegro
منابع مشابه
Role of environmental toxins in endemic (Balkan) nephropathy. October 2006, Zagreb, Croatia.
An international symposium, held in Zagreb, Croatia, in October 2006, brought together basic scientists and clinical investigators engaged in research on endemic (Balkan) nephropathy, a chronic renal tubulointerstitial disease of previously unknown cause that often is accompanied by upper urinary tract urothelial cancer. Although this disease is endemic in rural areas of Bosnia, Bulgaria, Croat...
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Balkan endemic nephropathy (BEN), originally described in 1956, is a unique familial, chronic renal disease encountered with a high-prevalence rate in Serbia, Bulgaria, Romania, Croatia and Bosnia and Herzegovina. The most prominent features of the disease are its endemic nature, long-incubation period, familial clustering of the disease and an unusually high incidence of associated upper uroth...
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In the first issue of BANTAO J, in 2003, I have presented the current research in Balkan endemic nephropathy (BEN) and associated upper urothelial tumors (UUT). As I stated in that paper, etiology remains the main problem for research in BEN [1]. Research of BEN in the nineties was hampered by the turmoil in the Balkans, especially in the former Yugoslavia. The Program Committee of the Interaca...
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Despite broad investigations into the possible role of genetic factors, environmental agents and immune mechanisms, the etiology of Balkan endemic nephropathy (BEN) is only partially understood. An increased incidence of upper urothelial cancer in patients with BEN and in populations from endemic settlements has been demonstrated. Genetic studies have landed support for genetic predisposition t...
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